A Furman, Phillip: search on Z-Library

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1

Activity and the metabolic activation pathway of the potent and selective hepatitis C virus pronucleotide inhibitor PSI-353661

Phillip A. Furman, Eisuke Murakami, Congrong Niu, Angela M. Lam, Christine Espiritu, Shalini Bansal, Haiying Bao, Tatiana Tolstykh, Holly Micolochick Steuer, Meg Keilman, Veronique Zennou, Nigel Bourn

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 896 KB

english, 2011

2

Nucleoside, Nucleotide, and Non-Nucleoside Inhibitors of Hepatitis C Virus NS5B RNA-Dependent RNA-Polymerase

Sofia, Michael J., Chang, Wonsuk, Furman, Phillip A., Mosley, Ralph T., Ross, Bruce S.

Journal:

Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 4.12 MB

english, 2012

3

Water Consumption by Institutions

Phillip E. Searcy and Thomas deS. Furman

Journal:

American Water Works Association

Year:

1961

Language:

english

File:

PDF, 764 KB

english, 1961

4

Water Consumption by Institutions

Searcy, Phillip E., Furman, Thomas deS.

Journal:

Journal - American Water Works Association

Year:

1961

Language:

english

File:

PDF, 428 KB

english, 1961

5

The selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine

Gertrude B. Elion, Phillip A. Furman, James A. Fyfe, Paulo de Miranda, Lilia Beauchamp, Howard J. Schaeffer

Journal:

Reviews in Medical Virology

Year:

1999

Language:

english

File:

PDF, 194 KB

english, 1999

6

Synthesis and Evaluation of a Novel Synthetic Phosphocholine Lipid-AZT Conjugate that Double-Targets Wild-Type and Drug Resistant Variants of HIV.

Louis S. Kucera, Susan L. Morris-Natschke, Khalid S. Ishaq, Jan Hes, Nathan Lyer, Phillip A. Furman, Ronald A. Fleming

Journal:

Year:

2004

File:

PDF, 80 KB

2004

7

Inhibition by acyclovir of herpes simplex virus type 2 morphologically transformed cell growth in tissue culture and tumor-bearing animals

Dr Louis S. Kucera, Phillip A. Furman, Gertrude B. Elion

Journal:

Journal of Medical Virology

Year:

1983

Language:

english

File:

PDF, 525 KB

english, 1983

8

Applied virology. Edited by Edouard Kurstak. Academic Press, Inc., Orlando, Florida. 1984. ISBN 0–12–429601–7. $59.00

Journal:

Journal of Pharmaceutical Sciences

Year:

1986

Language:

english

File:

PDF, 257 KB

english, 1986

9

Synthesis and antiviral activity of 2′-deoxy-2′-fluoro-2′-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication

Jeremy L. Clark, J. Christian Mason, Laurent Hollecker, Lieven J. Stuyver, Phillip M. Tharnish, Tamara R. McBrayer, Michael J. Otto, Phillip A. Furman, Raymond F. Schinazi, Kyoichi A. Watanabe

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 113 KB

english, 2006

10

Synthesis and anti-HCV activity of 3′,4′-oxetane nucleosides

Wonsuk Chang, Jinfa Du, Suguna Rachakonda, Bruce S. Ross, Serge Convers-Reignier, Wei T. Yau, Jean-Francois Pons, Eisuke Murakami, Haiying Bao, Holly Micolochick Steuer, Phillip A. Furman, Michael J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 444 KB

english, 2010

11

Phenylpropenamide derivatives: Anti-hepatitis B virus activity of the Z isomer, SAR and the search for novel analogs

Peiyuan Wang, Devan Naduthambi, Ralph T. Mosley, Congrong Niu, Phillip A. Furman, Michael J. Otto, Michael J. Sofia

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.70 MB

english, 2011

12

Synthesis, anti-human immunodeficiency virus, and anti-hepatitis B virus activity of pyrimidine oxathiolane nucleosides

Woo-Baeng Choi, Suresh Yeola, Dennis C. Liotta, Raymond F. Schinazi, George R. Painter, Michelle Davis, Marty St. Clair, Phillip A. Furman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 341 KB

english, 1993

13

The synthesis and anti-hiv activity of pyrimidine dioxolanyl nucleosides

Lawrence J. Wilson, Woo-Baeg Choi, Travis Spurling, Dennis C. Liotta, Raymond F. Schinazi, Deborah Cannon, George R. Painter, Marty St. Clair, Phillip A. Furman

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 448 KB

english, 1993

14

Sudden Death Mortality in Implantable Cardioverter Defibrillator Patients

JAY GROSS, PHILLIP ZILO, KEVIN FERRICK, JOHN D. FISHER, SEYMOUR FURMAN

Journal:

Pacing and Clinical Electrophysiology

Year:

1991

Language:

english

File:

PDF, 1.79 MB

english, 1991

15

Synthesis and Evaluation of a Novel Synthetic Phosphocholine Lipid‐AZT Conjugate That Double‐Targets Wild‐Type and Drug Resistant Variants of HIV

Kucera, Louis S., Morris‐Natschke, Susan L., Ishaq, Khalid S., Hes, Jan, Iyer, Nathan, Furman, Phillip A., Fleming, Ronald A.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2004

Language:

english

File:

PDF, 313 KB

english, 2004

16

Enterotoxin-producing staphylococci cause intestinal inflammation by a combination of direct epithelial cytopathy and superantigen-mediated T-cell activation

Lindsey A. Edwards, Colette O'Neill, Mark A. Furman, Susan Hicks, Franco Torrente, Miguel Pérez-Machado, Elizabeth M. Wellington, Alan D. Phillips, Simon H. Murch

Journal:

Inflammatory Bowel Diseases

Year:

2012

Language:

english

File:

PDF, 2.21 MB

english, 2012

17

Development of novel therapies for hepatitis C

Stanley M. Lemon, Jane A. McKeating, Thomas Pietschmann, David N. Frick, Jeffrey S. Glenn, Timothy L. Tellinghuisen, Julian Symons, Phillip A. Furman

Journal:

Antiviral Research

Year:

2010

Language:

english

File:

PDF, 1.63 MB

english, 2010

18

In vitro Selection of HCV Replicons with Reduced Sensitivity to PSI-352938, A Cyclicphosphate Prodrug of β-d-2′-α-F-2′-β-C-Methylguanosine

Angela M. Lam, Christine Espiritu, Shalini Bansal, Holly M. Micolochick Steuer, Veronique Zennou, Michael J. Otto, Phillip A. Furman

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

19

A Comparison of the ability of wild-type and S282T mutant HCV NS5B to incorporate 2′-α-F-2′-β-C-methylguanosine-5′-monophosphate and 2′-α-OH-2′-β-C-methylguanosine-5′-monophosphate

Eisuke Murakami, Haiying Bao, Angela M. Lam, Christine Espiritu, Shalini Bansal, Phillip A. Furman

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 76 KB

english, 2011

20

Adenosine Deaminase-like Protein 1 (ADAL1) Catalyzes Removal of Different Alkyl Groups from N6- or O6-substituted Purine or 2-Aminopurine Nucleoside Monophosphates

Eisuke Murakami, Haiying Bao, Ralph Mosely, Jinfa Du, Michael J. Sofia, Phillip A. Furman

Journal:

Antiviral Research

Year:

2011

Language:

english

File:

PDF, 87 KB

english, 2011

21

Inhibition of hepatitis C virus NS5A by fluoro-olefin based γ-turn mimetics

Wonsuk Chang, Ralph T. Mosley, Shalini Bansal, Meg Keilman, Angela M. Lam, Phillip A. Furman, Michael J. Otto, Michael J. Sofia

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 490 KB

english, 2012

22

Effect of acyclovir on the deoxyribonucleoside triphosphate pool levels in Vero cells infected with herpes simplex virus type 1

Phillip A. Furman, Catherine U. Lambe, Donald J. Nelson

Journal:

The American Journal of Medicine

Year:

1982

Language:

english

File:

PDF, 436 KB

english, 1982

23

Biochemical and genetic analysis of acyclovir-resistant mutants of herpes simplex virus type 1

Donald M. Coen, Priscilla A. Schaffer, Phillip A. Furman, Paul M. Keller, Marty H.St. CLAIR

Journal:

The American Journal of Medicine

Year:

1982

Language:

english

File:

PDF, 1.20 MB

english, 1982

24

Acyclovir inhibition of viral DNA chain elongation in herpes simplex virus-infected cells

Paul V. McGuirt, Phillip A. Furman

Journal:

The American Journal of Medicine

Year:

1982

Language:

english

File:

PDF, 389 KB

english, 1982

25

Effects of 3′-azido-3′-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells

Lloyd W. Frick, Donald J. Nelson, Marty H. St. Clair, Phillip A. Furman, Thomas A. Krenitsky

Journal:

Biochemical and Biophysical Research Communications

Year:

1988

Language:

english

File:

PDF, 430 KB

english, 1988

26

Investigation of the stereochemical course of DNA synthesis catalysed by human immunodeficiency virus type 1 reverse transcriptase

Sam Hopkins, Phillip A. Furman, George R. Painter

Journal:

Biochemical and Biophysical Research Communications

Year:

1989

Language:

english

File:

PDF, 366 KB

english, 1989

27

Crosslinking of substrates occurs exclusively to the p66 subunit of heterodimeric HIV-1 reverse transcriptase

Nancy Cheng, George R. Painter, Phillip A. Furman

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 740 KB

english, 1991

28

Enzymatic phosphorylation of acyclic nucleoside analogs and correlations with antiherpetic activities

Paul M. Keller, James A. Fyfe, Lilia Beauchamp, Carol M. Lubbers, Phillip A. Furman, Howard J. Schaeffer, Gertrude B. Elion

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 681 KB

english, 1981

29

Purification and kinetic characterization of equine infectious anemia virus reverse transcriptase

Deborah A. Thomas, Phillip A. Furman

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 411 KB

english, 1991

30

Inhibition by acyclovir of cell growth and DNA synthesis of cells biochemically transformed with Herpesvirus genetic information

Phillip A. Furman, Paul V. McGuirt, Paul M. Keller, James A. Fyfe, Gertrude B. Elion

Journal:

Year:

1980

Language:

english

File:

PDF, 923 KB

english, 1980

31

Cytostatic 6-Arylpurine Nucleosides. 6. † SAR in Anti-HCV and Cytostatic Activity of Extended Series of 6-Hetarylpurine Ribonucleosides

Hocek, Michal, Nauš, Petr, Pohl, Radek, Votruba, Ivan, Furman, Phillip A., Tharnish, Phillip M., Otto, Michael J.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 107 KB

english, 2005

32

A 2′-Deoxy-2′-Fluoro-2′-C-Methyl Uridine Cyclopentyl Carbocyclic Analog and Its Phosphoramidate Prodrug as Inhibitors of HCV NS5B Polymerase

Liu, Jian, Du, Jinfa, Wang, Peiyuan, Nagarathnam, Dhanapalan, Espiritu, Christine L., Bao, Haiying, Murakami, Eisuke, Furman, Phillip A., Sofia, Michael J.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2012

Language:

english

File:

PDF, 196 KB

english, 2012

33

Synthesis of Stable Isotope Labeled Analogs of the Anti-Hepatitis C Virus Nucleotide Prodrugs PSI-7977 and PSI-352938

Chun, Byoung-Kwon, Du, Jinfa, Zhang, Hai-Ren, Chang, Wonsuk, Ross, Bruce S., Jiang, Ying, Bao, Donghui, Espiritu, Christine L., Keilman, Meg, Steuer, Holly M. Micolochick, Furman, Phillip A., Sofia, M

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2011

Language:

english

File:

PDF, 270 KB

english, 2011

34

Adenosine Deaminase-like Protein 1 (ADAL1): Characterization and Substrate Specificity in the Hydrolysis of N 6 - or O 6 -Substituted Purine or 2-Aminopurine Nucleoside Monophosphates

Murakami, Eisuke, Bao, Haiying, Mosley, Ralph T., Du, Jinfa, Sofia, Michael J., Furman, Phillip A.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 4.95 MB

english, 2011

35

Clevudine: a potent inhibitor of hepatitis B virus in vitro and in vivo

Korba, Brent E, Furman, Phillip A, Otto, Michael J

Journal:

Expert Review of Anti-infective Therapy

Year:

2006

Language:

english

File:

PDF, 472 KB

english, 2006

36

Use of 2′-Spirocyclic Ethers in HCV Nucleoside Design

Du, Jinfa, Chun, Byoung-Kwon, Mosley, Ralph T., Bansal, Shalini, Bao, Haiying, Espiritu, Christine, Lam, Angela M., Murakami, Eisuke, Niu, Congrong, Micolochick Steuer, Holly M., Furman, Phillip A., S

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 768 KB

english, 2014

37

Linear stapler technique for creation of the gastrojejunostomy in laparoscopic Roux-en-Y gastric bypass results in minimal rate of anastomotic stricture

Lyass, Sergey, Burch, Miguel, Misra, Monali, Hagiike, Masanobu, Cunneen, Scott A., Furman, Gary, Phillips, Edward H., Khalili, Theodore M.

Journal:

Surgery for Obesity and Related Diseases

Year:

2005

Language:

english

File:

PDF, 42 KB

english, 2005

38

Reduced in vivo Mutagenesis by Mutant Herpes Simplex DNA Polymerase Involves Improved Nucleotide Selection

Jennifer D. Hall, Phillip A. Furman, Marty H. St. Clair and Charles W. Knopf

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 852 KB

english, 1985

39

Potentiation of Antiherpetic Activity of Acyclovir by Ribonucleotide Reductase Inhibition

Thomas Spector, Devron R. Averett, Donald J. Nelson, Catherine U. Lambe, Robert W. Morrison, Marty H. St. Clair and Phillip A. Furman

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 635 KB

english, 1985

40

Phosphorylation of 3′-azido-3′-deoxythymidin e and Selective Interaction of the 5′-triphosphate with Human Immunodeficiency Virus Reverse Transcriptase

Phillip A. Furman, James A. Fyfe, Marty H. St. Clair, Kent Weinhold, Janet L. Rideout, George A. Freeman, Sandra Nusinoff Lehrman, Dani P. Bolognesi, Samuel Broder, Hiroaki Mitsuya and David W. Barry

Journal:

Proceedings of the National Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 366 KB

english, 1986

41

Selectivity of Action of an Antiherpetic Agent, 9-(2-hydroxyethoxymethyl)guanine

Gertrude B. Elion, Phillip A. Furman, James A. Fyfe, Paulo De Miranda, Lilia Beauchamp and Howard J. Schaeffer

Journal:

Proceedings of the National Academy of Sciences

Year:

1977

Language:

english

File:

PDF, 961 KB

english, 1977

42

Paneth cell metaplasia in newly diagnosed inflammatory bowel disease in children

Simmonds, Naomi, Furman, Mark, Karanika, Evi, Phillips, Alan, Bates, Alan WH

Journal:

BMC Gastroenterology

Year:

2014

Language:

english

File:

PDF, 911 KB

english, 2014

43

Conformation and Local Environment of Nucleotides Bound To Hiv Type 1 Reverse Transcriptase (HIV-1 RT) in The Ground State

Painter, George R., Andrews, C. Webster, Furman, Phillip A.

Journal:

Nucleosides Nucleotides & Nucleic Acids

Year:

2000

Language:

english

File:

PDF, 796 KB

english, 2000

44

Lysing Bacterial Spores by Sonication through a Flexible Interface in a Microfluidic System

Taylor, Michael T., Belgrader, Phillip, Furman, Burford J., Pourahmadi, Farzad, Kovacs, Gregory T. A., Northrup, M. Allen

Journal:

Analytical Chemistry

Year:

2001

Language:

english

File:

PDF, 270 KB

english, 2001

45

Identification of the nucleotide binding site of HIV-1 reverse transcriptase using dTTP as a photoaffinity label

Cheng, Nancy, Merrill, Barbara M., Painter, George R., Frick, Lloyd W., Furman, Phillip A.

Journal:

Year:

1993

Language:

english

File:

PDF, 1.06 MB

english, 1993

46

An Analysis of the Catalytic Cycle of HIV-1 Reverse Transcriptase Opportunities for Chemotherapeutic Intervention Based on Enzyme Inhibition

Furman, Phillip, Painter, George, Anderson, Karen

Journal:

Current Pharmaceutical Design

Year:

2000

Language:

english

File:

PDF, 711 KB

english, 2000

47

Nucleoside analog inhibitors of hepatitis C viral replication: recent advances, challenges and trends

Furman, Phillip A, Lam, Angela M, Murakami, Eisuke

Journal:

Future Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 1.49 MB

english, 2009

48

Chemotherapy of herpesvirus infections

Furman, Phillip A.

Journal:

Current Eye Research

Year:

1987

Language:

english

File:

PDF, 646 KB

english, 1987

49

Teaching Conversational Skills to Retarded Adolescents

Kelly, Jeffrey A., Furman, Wyndol, Phillips, Jody, Hathorn, Sue, Wilson, Terry

Journal:

Child Behavior Therapy

Year:

1979

Language:

english

File:

PDF, 622 KB

english, 1979

50

Mutations in the herpes simplex virus DNA polymerase gene conferring hypersensitivity to aphidicolin

Coen, Donald M., Furman, Phillip A., Aschman, Doris P., Schaffer, Priscilla A.

Journal:

Nucleic Acids Research

Year:

1983

Language:

english

File:

PDF, 447 KB

english, 1983

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